Platelet Rich Fibrin (PRF) or Leukocyte-Platelet Rich Fibrin (L-PRF) is a 3-D autogenous combination of Platelet Rich Fibrin derived from the patient’s blood. A simplified chairside procedure results in the production of a thin, compressed layer of platelet rich fibrin that is strong, pliable and suitable for suturing. This natural fibrin network is rich in platelets, growth factors and cytokines that are derived from the blood platelets and leukocytes. The presence of these proteins have been reported to produce rapid healing, especially during the critical first seven days after placement. This network promotes more efficient cell migration and proliferation without chemical or bovine thrombin additives.
Some of the benefits of using L-PRF are:
• Simple and economic.
• Natural - 100% autologous.
• Increasing healing process.
• Reduction of healing times.
• Decreases chances of post operative complications.
• Matrix for Bone Graft Material.
Clinically, Leukocyte-Platelet Rich Fibrin displays excellent working properties. This biomaterial is resilient, strong and pliable, making it easy to manipulate. It can be cut to size, and is supple enough to adapt to many anatomical areas. It is adhesive in nature and very receptive to suturing. In addition, there is ample working time since PRF/L-PRF is stable at room temperature for several hours.